Reduction of Intracellular Chloride Concentration Promotes Foam Cell Formation
نویسندگان
چکیده
منابع مشابه
Decrease of intracellular chloride concentration promotes endothelial cell inflammation by activating nuclear factor-κB pathway.
Recent evidence suggested that ClC-3 channel/antiporter is involved in regulation of nuclear factor (NF)-κB activation. However, the mechanism explaining how ClC-3 modulates NF-κB signaling is not well understood. We hypothesized that ClC-3-dependent alteration of intracellular chloride concentration ([Cl(-)](i)) underlies the effect of ClC-3 on NF-κB activity in endothelial cells. Here, we fou...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2016
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-15-1209